Thursday, April 13, 2023

The lasting anguish of moral injury

Psychologists are finding that moral code violations can leave an enduring mark — and may require new types of therapy

On a Sunday evening in September 1994, David Peters drove to a church service in Beckley, West Virginia, as the sun set over the horizon. He was 19 years old, just back from Marine Corps boot camp. He hadn’t been behind the wheel of a car all summer.

The road curved, and Peters misjudged the turn. Rays from the dipping sun blinded him. The car hit the median and headed straight at an oncoming motorcycle. And then, Peters says, “Everything went crash.”

His friend, sitting in the passenger seat, seemed fine. Peters got out of the car. The driver of the motorcycle was alive, but the woman who’d been riding behind him was now laid out on the pavement. Peters quickly realized she was dead.

Now an Episcopal priest in Pflugerville, Texas, outside Austin, Peters says there have been periods during the last 28 years when he’s found the knowledge that he killed someone almost unbearable. “I felt like I wasn’t good anymore,” he says. At times, he even wished he were dead. Years after the accident, he purchased a motorcycle, thinking “that'd be sort of justice if I died on a motorcycle.” 

Peters may have experienced what some psychologists and researchers have begun to call “moral injury,” a concept introduced by a psychiatrist to describe the devastation he witnessed in Vietnam War veterans and others who believed they’d been ordered to act in ways that violated their personal moral code. The term encompasses a constellation of signs and symptoms that go beyond mere guilt and shame and can be so severe that people lose a sense of their own goodness and trustworthiness, leading to drastic impacts on daily functioning and quality of life. 

Moral injury results from “the way that humans make meaning out of the violence that they have either experienced or that they have inflicted,” says Janet McIntosh, an anthropologist at Brandeis University who wrote about the psychic wounds resulting from how we use language when talking about war in the 2021  Annual Review of Anthropology

Although research on moral injury began with the experiences of veterans and active-duty military, it has expanded in recent years to include civilians. The pandemic — with its heavy moral burdens on health care workers and its fraught decisions over gathering in groups, masking and vaccinating — intensified scientific interest in how widespread moral injury might be. “What’s innovative about moral injury is its recognition that our ethical foundations are essential to our sense of self, to our society, to others, to our professions,” says Daniel Rothenberg, who codirects the Center on the Future of War at Arizona State University.

Yet moral injury remains a concept under construction. It is not an official diagnosis in psychiatry’s authoritative guide, the Diagnostic and Statistical Manual of Mental Disorders (DSM). And until the recent publication of a major study on the subject, researchers and clinicians lacked well-defined criteria they could use to determine if someone has moral injury, says Brett Litz, a clinical psychologist at VA Boston Health Care System and Boston University. “The prevalence of moral injury is utterly unknown, because we haven’t had a gold standard measure of it,” he says. 

‘It starts working on your head’

Moral injury was first described by Jonathan Shay, a psychiatrist in Boston, who defined it as a sense of “betrayal of what’s right, by someone who holds legitimate authority (in the military — a leader), in a high-stakes situation.” In his 1994 book, Achilles in Vietnam, Shay quotes a soldier whose platoon fired on people at the beach one night, having been told by commanders that their targets were unloading weapons. But when daylight came, the soldiers realized they’d killed a bunch of fishermen and their children. “So it starts working on your head,” the soldier told Shay. “So you know in your heart it’s wrong, but at the time, here’s your superiors telling you that it was OK.” Incidents like this, Shay argued, are not just upsetting, but also damaging.

As the years passed, some researchers felt that Shay’s definition focused too narrowly on betrayal by leaders or country. In 2009, Litz and colleagues expanded the definition to include more personal types of moral injury, such as the lasting impact of “perpetrating, failing to prevent, bearing witness to, or learning about acts that transgress deeply held moral beliefs and expectations.” 

In a 2019 study, researchers devised a list of potentially morally injurious events to civilians by reviewing previous literature and research, as well as consulting experts and people who suffered from memories of morally distressing events. The researchers came up with 31 events that seemed to distress people enough to lead to moral injury, including a car accident while texting, sexual assault, working within a corrupt organization, witnessing abuse of power at work, cheating on a romantic partner and stopping providing for dependent children. But not everyone reacts to troubling events in the same way, and not everyone who experiences a particular event will suffer a moral injury, says study coauthor Matt Gray, a clinical psychologist at the University of Wyoming. What really makes a difference, he says, is “people’s moral framework and their appraisal of their actions or inactions.”

Because such actions and encounters can be traumatic, people with moral injury may appear to have post-traumatic stress disorder. But a diagnosis of PTSD does not capture the entirety of this kind of suffering, Shay and therapists who came after have found.

Many researchers view PTSD and moral injury as distinct conditions, although they overlap in their symptoms and the types of events that trigger them. PTSD is characterized by anxiety that develops after a serious physical threat of injury, sexual violence or death. But that triggering event doesn’t necessarily have to be morally injurious — it could be a natural disaster, say. For moral injury, on the other hand, the triggering event is always morally injurious but it may or may not involve a physical threat; it could be something like causing financial distress to others due to a gambling addiction.

Both conditions can involve intrusive memories of the traumatic event, avoidance of reminders of the event, lack of interest in pleasurable activities and detachment from others, Litz and colleagues wrote recently in  Frontiers in Psychiatry  (some researchers have categorized the overlapping symptoms differently). But moral injury is more likely to lead to other symptoms, Litz says, including alterations in self-perception, loss of meaning and loss of religious faith. 

The two conditions may have different effects on the brain. In a 2016 study, active-duty military personnel seeking trauma treatment were asked to lie in a darkened room with their eyes closed for 30 minutes, after which they underwent a brain scan. Those who had been traumatized by a physical threat exhibited elevated resting neuronal activity in their right amygdala, a part of the brain associated with emotional responses, particularly fear. But those who were haunted by something they did or witnessed had more activity in their left precuneus, a part of the brain that is related to sense of self.

Over time, the moral injury research lens has expanded to include nonmilitary populations such as police officersteachersrefugees and  journalists. One 2019 study, for instance,  surveyed teachers and other K-12 professionals in an urban Midwest school district, where some schools were white and affluent, some were racially and economically mixed, and others were largely made up of impoverished students of color. The less affluent and the more segregated the students, the more likely the teachers were to experience moral injury, writes the study’s author, Erin Sugrue, a social worker at Augsburg University in Minneapolis. “Professionals in these schools may experience moral injury as they come into close contact with the impact of racism and income inequality, two inherently immoral social forces, on the daily lives of their students.” 

During the pandemic, researchers have turned their focus to the medical front lines. One recent study led by Jason Nieuwsma, a clinical psychologist at Duke University School of Medicine, analyzed data from a March 2021 survey of health care workers. They  reported potentially morally injurious experiences that included hospital policies that  prohibited dying patients from receiving visitors, watching some people refuse to wear masks to protect those who were more vulnerable, and being too overworked to provide optimal care. One wrote: “My line in the sand was treating patients in wheelchairs outside in the ambulance bay in the cold fall night. I got blankets and food for people outside with IV fluid running. I was ashamed of the care we were providing.”

Roughly half of the health care workers reported they were troubled by witnessing others’ immoral acts, and just under a fifth (18.2 percent) reported that they were troubled by having acted in ways that violated their own morals and values. “It begs the question of whether that experience will persist over time,” Nieuwsma says. “It’s something health care systems need to pay attention to.”

Still, Nieuwsma, who has largely studied moral injury in a military context, says he and other researchers have been reluctant to apply the term to the civilian population. “We want to preserve the intensity” of the description, he says.

To distinguish between normal moral stress and abnormal distress at levels that may require therapeutic intervention, Litz and Patricia Kerig, a clinical psychologist at the University of Utah, propose a moral continuum. At one end is the kind of moral frustration one might experience over an upcoming local or national election, events that are not immediately personal. Then there are more distressing events involving a personal, moral transgression (like if you behave hurtfully to someone you love or steal someone else’s idea). A person may lose sleep over such issues, but they are not disabling and do not define the person in question. At the far end of the spectrum is the type of debilitating moral injury that consumes a person with intense guilt or shame.

But what exactly are the parameters of that injury? So far researchers and clinicians have lacked an objective measure of moral injury. To rectify that, Litz and 10 colleagues, along with a broad consortium of other experts, recently sent questionnaires to hundreds of active-duty service members and military veterans in the United States, Canada, the United Kingdom, Australia and Israel who had suffered potentially morally injurious experiences. From their responses, the researchers identified 14 reactions that indicate the presence of moral injury. The list includes statements like “I have lost pride in myself” and “I am disgusted by what happened.” The researchers believe their new “moral injury outcome scale,” will be a useful tool for future studies.

Forward-looking therapy

Nearly 30 years ago, Shay saw that a diagnosis of PTSD didn’t encompass all that Vietnam veterans were dealing with. And today, psychologists recognize that the treatments don’t directly translate, either. Treatment for PTSD typically involves drugs that treat depression and anxiety, as well as therapy intended to help patients reframe negative thoughts about the trauma and gain control by facing negative feelings. With PTSD, “we’re trying to reappraise and reinterpret and recontextualize that event, and we’re trying to get you, in the here and now, not to be as reactive to it,” says Gray. In a sense, such therapy is “backwards-acting,” he says. 

For someone struggling with moral injury, however, it may not be possible to recontextualize the inciting event, because in some cases it’s truly what it appears to be: a violation of a person’s moral code. As a result, Gray says, therapy for moral injury needs to be forward-looking, or what he, Litz and colleagues describe in a 2017 book as “adaptive disclosure.” 

This form of therapy attempts to help the patient come to terms with their moral injury by shifting their perspective. A patient may blame themselves or others for what went wrong, and this may be objectively true, the authors write. But in therapy, the patient can be encouraged to take ownership of the act; consider forgiving themselves; commit to actions that have real or symbolic reparative value (such as someone who harmed another by driving while drunk agreeing to speak to high school students about the dangers of mixing driving and alcohol consumption); and recognizing that condemning themselves for the horrific act cannot erase it, but can prevent them from doing good in the world going forward. It essentially tells the person, “You have things that you can still contribute, and that ultimately will be more productive and more meaningful than just isolation and self-loathing,” Gray says.

If this sounds a lot like traditional religious teachings, that’s not far off, says Harold G. Koenig, a psychiatrist at Duke University School of Medicine. “This is something that religions have dealt with, and continue to deal with, since the beginning of time,” he says. Koenig and colleagues have been developing what he calls “spiritually integrated” therapies for moral injury based on the scriptures of the world’s major religious traditions, as well as interventions designed specifically for chaplains to help them treat people of any faith or even those without a faith. 

One example of the latter intervention is called “pastoral narrative disclosure.” It’s based on the idea that confession and absolution are key to redemption. As described in a 2018 paper, it involves helping the patient reflect on what happened, attempting to place it within the context of the person’s entire life, and then creating an absolution ritual that has spiritual meaning for the patient.

As for Peters, he’s connected with a support group of people who have accidentally killed someone, and he’s writing a book to help others in his position. He’s also taken comfort in the concept of a  city of refuge, described in the Old Testament as a place for accidental murderers to stay safe from possible avengers. “I had to build a city of refuge for myself,” Peters says. 

His “city” includes art, theology, the comfort derived from the community he found online and a mission to reduce dependence on cars. It’s a place, he says, “where I am able to live, but also live with the awareness that I’ve done this thing.” 

This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.

Wednesday, April 12, 2023

Jupiter’s moons hide giant subsurface oceans – two upcoming missions are sending spacecraft to see if these moons could support life

The surface of Europa – one of Jupiter’s moons – is a thick layer of solid ice. NASA/JPL-Caltech/SETI Institute, CC BY-SA
Mike Sori, Purdue University

On April 13, 2023, the European Space Agency is scheduled to launch a rocket carrying a spacecraft destined for Jupiter. The Jupiter Icy Moons Explorer – or JUICE – will spend at least three years on Jupiter’s moons after it arrives in 2031. In October 2024, NASA is also planning to launch a robotic spacecraft named Europa Clipper to the Jovian moons, highlighting an increased interest in these distant, but fascinating, places in the solar system.

I’m a planetary scientist who studies the structure and evolution of solid planets and moons in the solar system.

There are many reasons my colleagues and I are looking forward to getting the data that JUICE and Europa Clipper will hopefully be sending back to Earth in the 2030s. But perhaps the most exciting information will have to do with water. Three of Jupiter’s moons – Europa, Ganymede and Callisto – are home to large, underground oceans of liquid water that could support life.

Four moons next to a large red spot on the surface of Jupiter.
This composite image shows, from top to bottom, Io, Europa, Ganymede and Callisto next to Jupiter. NASA, CC BY-ND

Meet Io, Europa, Ganymede and Callisto

Jupiter has dozens of moons. Four of them in particular are of interest to planetary scientists.

Io, Europa, Ganymede and Callisto are, like Earth’s Moon, relatively large, spherical complex worlds. Two previous NASA missions have sent spacecraft to orbit the Jupiter system and collected data on these moons. The Galileo mission orbited Jupiter from 1995 to 2003 and led to geological discoveries on all four large moons. The Juno mission is still orbiting Jupiter today and has provided scientists with an unprecedented view into Jupiter’s composition, structure and space environment.

These missions and other observations revealed that Io, the closest of the four to its host planet, is abuzz with geological activity, including lava lakes, volcanic eruptions and tectonically formed mountains. But it is not home to large amounts of water.

Europa, Ganymede and Callisto, in contrast, have icy landscapes. Europa’s surface is a frozen wonderland with a young but complex history, possibly including icy analogs of plate tectonics and volcanoes. Ganymede, the largest moon in the entire solar system, is bigger than Mercury and has its own magnetic field generated internally from a liquid metal core. Callisto appears somewhat inert compared to the others, but serves as a valuable time capsule of an ancient past that is no longer accessible on the youthful surfaces of Europa and Io.

Most exciting of all: Europa, Ganymede and Callisto all almost certainly possess underground oceans of liquid water.

A diagram showing a cutaway of Europa.
Warmth from Europa’s interior and tidal energy from Jupiter likely maintain a massive liquid ocean beneath the moon’s icy surface. NASA/JPL-Caltech/Michael Carroll

Ocean worlds

Europa, Ganymede and Callisto have chilly surfaces that are hundreds of degrees below zero. At these temperatures, ice behaves like solid rock.

But just like Earth, the deeper underground you go on these moons, the hotter it gets. Go down far enough and you eventually reach the temperature where ice melts into water. Exactly how far down this transition occurs on each of the moons is a subject of debate that scientists hope to resolve with JUICE and Europa Clipper. While the exact depths are still uncertain, scientists are confident that these oceans exist.

The best evidence of these oceans comes from Jupiter’s magnetic field. Saltwater is electrically conductive. So as these moons travel through Jupiter’s magnetic field, they generate a secondary, smaller magnetic field that signals to researchers the presence of an underground ocean. Using this technique, planetary scientists have been able to show that the three moons contain underground oceans. And these oceans are not small – Europa’s ocean alone might have more than double the water of all of Earth’s oceans combined.

An obvious and tantalizing next question is whether these oceans can support extraterrestrial life. Liquid water is an important piece of what makes for a habitable world, but far from the only requirement for life. Life also needs energy and certain chemical compounds in addition to water to flourish. Because these oceans are hidden beneath miles of solid ice, sunlight and photosynthesis are out. But it’s possible other sources could provide the needed ingredients.

On Europa, for example, the liquid water ocean overlays a rocky interior. That rocky seafloor could provide energy and chemicals through underwater volcanoes that could make Europa’s ocean habitable. But it is also possible that Europa’s ocean is a sterile, inhospitable place – scientists need more data to answer these questions.

Artist's impression of the JUICE spacecraft approaching Jupiter and the jovian moons.
The Jupiter Icy Moons Explorer spacecraft will travel for eight years before reaching Jupiter. ESA/ATG medialab/NASA/JPL/University of Arizona/J. Nichols

Upcoming missions from ESA and NASA

JUICE and Europa Clipper are set up to give scientists game-changing information about the potential habitability of Jupiter’s moons. While both missions will gather data on multiple moons, JUICE will spend time orbiting and focusing on Ganymede, and Europa Clipper will make dozens of close flybys of Europa.

Both of the spacecraft will carry a suite of scientific instruments built specifically to investigate the oceans. Onboard radar will allow JUICE and Europa Clipper to probe into the moons’ outer layers of solid ice. Radar could reveal any small pockets of liquid water in the ice, or, in the case of Europa, which has a thinner outer ice layer than Ganymede and Callisto, hopefully detect the larger ocean.

Magnetometers will also be on both missions. These tools will give scientists the opportunity to study the secondary magnetic fields produced by the interaction of conductive oceans with Jupiter’s field in great detail and will hopefully give researchers clues to salinity and volumes of the oceans.

Scientists will also observe small variations in the moons’ gravitational pulls by tracking subtle movements in both spacecrafts’ orbits, which could help determine if Europa’s seafloor has volcanoes that provide the needed energy and chemistry for the ocean to support life.

Finally, both craft will carry a host of cameras and light sensors that will provide unprecedented images of the geology and composition of the moons’ icy surfaces.

Maybe one day, a spacecraft will be able to drill through the miles of solid ice on Europa, Ganymede or Callisto and explore oceans directly. Until then, observations from spacecraft like JUICE and Europa Clipper are scientists’ best bet for learning about these ocean worlds.

When Galileo discovered these moons in 1609, they were the first objects known to directly orbit another planet. Their discovery was the final nail in the coffin of the theory that Earth – and humanity – resides at the center of the universe. Maybe these worlds have another humbling surprise in store.

Mike Sori, Assistant Professor of Planetary Science, Purdue University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

The race against radon

Scientists are working to map out the risks of the permafrost thaw, which could expose millions of people to the invisible cancer-causing gas

Deep in the frozen ground of the north, a radioactive hazard has lain trapped for millennia. But UK scientist Paul Glover realized some years back that it wouldn’t always be that way: One day it might get out. 

Glover had attended a conference where a speaker described the low permeability of permafrost — ground that remains frozen for at least two years or, in some cases, thousands. It is an icy shield, a thick blanket that locks contaminants, microbes and molecules below foot — and that includes the cancer-causing radioactive gas radon.

“It immediately occurred to me that, well, if there is radon underground, it will be trapped there by a layer of permafrost,” recalls Glover, a petrophysicist at the University of Leeds in England. “What happens if that layer suddenly isn’t there anymore?” Ever since then, Glover has worked on methods to estimate how much radon — which is released as the element radium decays — might be liberated as climate change causes the permafrost to thaw. 

Significant areas of Arctic and sub-Arctic ground  contain permafrost — but today it is melting, and the rate of that thaw is accelerating. In  a report published in January, Glover and coauthor Martin Blouin, now technical director at the mapping software firm Geostack, used modeling techniques to show that homes with basements built on areas of permafrost could be exposed to high levels of radon gas in the future. “As the permafrost melts, this reservoir of active radon can flood to the surface and get into buildings — and by being in buildings, cause a health hazard,” Glover says.

No one knows exactly how quickly radon diffuses through icy ground, but by using the rate of diffusion of carbon dioxide and adjusting for the properties of radon, Glover came up with a figure that he could use in the model. Based on 40 percent permafrost thaw, the calculations reveal that radon emissions could raise radioactivity levels to more than 200 becquerels per meter cubed (Bq/m3) for a period of more than four years in homes with basements at or below ground level. This happens when the 40 percent thaw occurs in 15 years or less.

According to the World Health Organization, the risk of lung cancer increases by about 16 percent with every 100 Bq/m3 of long-term exposure. Some countries,  including the UK, set the safe level of average exposure at 200 Bq/m3. But without testing for radon in areas where the geology suggests it’s present, people will not know whether they are at risk — because the gas is odorless, colorless and tasteless.

Glover stresses that the model in the paper is an early attempt to understand how permafrost thaw could affect people’s exposure to the gas. It doesn’t, for example, account for seasonal variation in the rate of permafrost thaw or the effects of soil compaction when ice within it melts, something which could pump yet more radon to the surface.

Some 3.3 million people live on permafrost that will have completely melted away by 2050, according to estimates in  a 2021 study. Not all of these people live in areas prone to radon but many do: For example, in parts of Canada, Alaska, Greenland and Russia. And the link between  radon exposure and lung cancer is well-established, as is the fact that  smoking further increases one’s risk, says Stacy Stanifer, oncology clinical nurse specialist at the University of Kentucky’s College of Nursing. She points to studies suggesting that radon  could be behind up to 1 in 10 lung cancer deaths, of which there are 1 million in total worldwide every year.

“Breathing radon is dangerous for everyone, but it’s even more harmful when you also breathe tobacco smoke,” says Stanifer. Smoking is prevalent in Arctic and sub-Arctic communities; for example, a 2012 study reported that nearly two-thirds of Canadian Inuit age 15 and over who live within the Inuit homeland said they smoke cigarettes daily, compared with 16 percent of Canadians overall.

Scientists don’t know how much radon is actually emanating from areas with melting permafrost today, says Nicholas Hasson, a geoscientist and PhD student at the University of Alaska Fairbanks: “I would call this a blank spot.” He notes that, in real life, permafrost layers are complex and irregular, and agrees with Glover that field measurements are essential to validate the model. Instead of a uniform sheet of ice underground, imagine permafrost as more of a higgledy-piggledy Swiss cheese of ice, with some areas much thicker than others and places where groundwater courses through it, exacerbating the thaw. 

Hasson and colleagues have studied locations where permafrost is thawing unusually quickly and emitting methane, a greenhouse gas many times more potent than carbon dioxide. Similar “chimneys” could be spewing out elevated amounts of radon gas in some places, he suggests.

For human health, what really matters is the amount of radon that gets into people’s homes. Scientists and even homeowners themselves can use radioactivity detectors to assess this. A study published online in February 2022, which is yet to be peer-reviewed, measured levels of radon over the course of a year in more than 250 homes in three towns in Greenland. Out of 59 homes in Narsaq, for instance, 17 were found to have radiation levels above 200 Bq/m3. 

Lead author Violeta Hansen, a radioecologist at Aarhus University in Denmark, stresses that these are early results based on a small number of homes. It would take much more research, she says, before she could evaluate the health risks associated with radon in properties like these across Greenland. She is now leading an international project that will run field experiments and gather radon measurements from homes in various countries, including Canada and Greenland. “We need to come back to the public with low-cost and effective, validated mitigation measures,” Hansen says.

It is important to avoid panicking people without solid data and solutions on hand, says Aaron Goodarzi, a radiobiologist at the University of Calgary in Canada. The good news is that there are tried-and-tested methods of lowering levels of radon inside a house once the homeowner knows it is there. Goodarzi points, for example, to a technique called sub slab depressurization, in which a sealed pipe is inserted below the house and connected to a fan. This sucks any radon out from below the building before blowing it away into the atmosphere. “Think of it simply like a bypass,” he says.

The type of building matters. Glover’s model found that homes built on piles or stilts, and thus separated from the ground, did not experience a boost in radon levels. Fortunately, many homes in the Arctic and sub-Arctic are constructed in this fashion. But for those that aren’t, the cost of mitigating radon could be prohibitive for low-income communities in these regions. “That’s an equity issue that has to be considered, certainly,” says Goodarzi, who notes that the onus might be on social housing administrators in some areas to ensure that the housing they provide is healthy.

A spokesperson for Health Canada says that the government agency currently recommends that homeowners test radon levels in their properties and use certified suppliers to install mitigation technologies if such are required.

Many people may not think about radon very much, given the fact that it is invisible. Glover says that getting informed now, before the permafrost thaw worsens, could save lives. 

“We know that people die from it,” he says. “But at the same time, there’s so much that we can do to protect ourselves.”

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This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.

OPINION: The reversal of Roe v. Wade is a tragedy not just for the United States, but for women everywhere

The past decades have brought modest improvements to women’s reproductive health around the world. Over the last 30 years, global rates of unintended pregnancies have thankfully declined by almost 20 percent, presumably in part because of better access to education and contraceptives. In 1973, the US Supreme Court, ruling in  Roe v. Wade, declared an American woman’s right to an abortion to be fundamental and constitutionally protected. This landmark decision helped inspire many countries around the world to enshrine the individual right to bodily autonomy in law or expand access to abortion services — including  Canada and  India. Many women have been able to access safe abortions and post-abortion care.

Then the 2022 US Supreme Court overturned Roe v. Wade

The ramifications of this reversal will be felt across the globe, threatening to set back modest policy gains, strengthen anti-abortion advocates and hamper progress in reproductive health and human rights.

Of course, unintended pregnancy is bound to happen. Sometimes, horrifically, it is the result of violence. From 2015 to 2019, there were 121 million unintended pregnancies a year on average — that’s 64 for every 1,000 women ages 15 to 49. This March, a study produced the  first global estimates of unintended pregnancy and abortion rates for 150 countries. In sub-Saharan Africa the rates are particularly high: In Uganda, unintended pregnancy affects 145 women per 1,000.

The important thing is whether these women have access to good information and health services. Many of them are increasingly seeking abortion: From 1990 to 2019, the rate of abortion for unintended pregnancies globally has increased from 51 percent to 61 percent. Not surprisingly, and appallingly, the new report notes that the rate of unsafe abortions is nearly 45 times higher in countries with highly restrictive abortion laws than in countries where abortion is legal and available.

Unsafe abortion is already one of the leading causes of maternal injury and death, killing an estimated 22,800 to 31,000 women annually worldwide. Every year, 7 million women suffer complications from unsafe abortions. This is entirely avoidable, but only with a supportive legal framework and a health system capable of delivering needed information and services.

Global advocates fear that the overturn of  Roe v. Wade will erode progress in that direction.

Already we have seen and heard alarming things in international meetings about women’s reproductive health that indicate a change in the tide. On July 19, for example, a UK-hosted joint multi-national human rights statement was amended, removing any mention of “abortion,” “sexual and reproductive health and rights” and “bodily autonomy” from the document. The advocacy group Humanists UK is protesting the change.

And Right to Life UK reports that India is now planning its first national March for Life for August; one of its organizers said she hopes the march will “carry on for years to come until the day the [Medical Termination of Pregnancy] Act is completely revoked just like  Roe v. Wade was revoked this year.”

A major concern is that power and funding will now increase for US-based anti-abortion groups that are already active in many countries around the world, including Human Life International, which has campaigned against contraception and abortion in sub-Saharan Africa for more than a decade; the East African Center for Law and Justice, a Christian organization with roots in the socially-conservative, anti-abortion American Center for Law and Justice; and Heartbeat International and Human Life International, two anti-abortion groups that have set up “crisis pregnancy centers” in practically every continent to dissuade women seeking abortions from terminating their pregnancies.

An emboldened anti-abortion movement is a threat to the hard-won gains in sexual and reproductive health and rights worldwide.

It is already hard for low-income nations to fund women’s reproductive health services. The use of US foreign aid funds specifically for the performance of an abortion as a method of family planning is illegal under the 1973 Helms Amendment (this July, Democratic senators introduced a bill attempting to repeal this amendment). And while the Bill and Melinda Gates Foundation, the major US private donor to global health, does  fund family planning programs, it does not fund abortion advocacy, information or services. This already makes it hard for countries that are significantly dependent on external funding for their health sector to provide safe abortion services and post-abortion care; the new court decision may make it even harder. 

The US Supreme Court’s decision blatantly ignores public health and the plethora of data that demonstrates the harms caused by these sorts of restrictions. We can only hope that other nations will learn from places where abortion is now safe and legal, such as Argentina, Ireland and, more recently, Sierra Leone, and stop turning to the US as a defender of human rights, or as an example of educated policymaking.

This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.

3 Health Care Trends for 2023

With many people preparing for health and wellness resolutions in the new year, understanding the state of access to care and other patients’ booking choices may give a sense of optimism for 2023.

To examine the outlook for 2023, Zocdoc, a free platform where people can find and book in-person or virtual health care appointments across more than 200 specialties and 12,000 insurance plans, analyzed appointment booking trends and conducted a provider survey. The results are reflected in the report, “Healthcare Hope For the Holidays: 2022,” which provided three key insights.

Happier Providers, Happier Patients
Provider and health care staff burnout can have a negative effect on patient experience, and 52% of providers surveyed indicated they agreed or strongly agreed practices will face increased financial challenges in 2023. However, savvy providers and support staff are taking steps to run more efficient practices, including using technology. This saves providers time and stress, giving them more time to focus on patient care.

In 2022, positivity pervaded providers’ perspectives on technology:

  • 64% of providers indicated they agreed or strongly agreed their scheduling software helped their practice run more efficiently.
  • 57% agreed or strongly agreed their telehealth solution was easy and intuitive to use.
  • 36% agreed or strongly agreed insurance verification and eligibility software helped their practice run more efficiently.

This perspective paints a positive picture for patient-provider relationships in 2023:

  • 71% of providers agreed or strongly agreed scheduling software will help run a more efficient practice.
  • 69% agreed or strongly agreed technology will help practices run more efficiently.
  • 59% agreed or strongly agreed their telehealth solution will become more intuitive and easier to use.

Technology Can Speed Up Access to Care
Amidst the unprecedented landscape of labor and supply costs rising, and physician and staff burnout a reality, innovation is driving positive change for patients. With a growing number of people embracing technology as a driver of access to an improved health care experience, and patients and providers aligned on telehealth as a supplement to in-person care, there are reasons for optimism.

Expediting patients’ access to care by surfacing the 20-30% of appointments that become available last minute due to cancellations and rescheduled appointments allows Zocdoc to enable faster speed-to-appointment for patients, compared to the averages reported in the Merritt Hawkins 2022 Survey of Physician Appointment Wait Times.

  • Cardiology: Typically 1-3 days with 39% seeing a cardiologist within 48 hours, compared to 26.6 days national average appointment wait time
  • Dermatology: Typically 1-3 days with nearly 30% seeing a dermatologist within 48 hours, compared to 34.5 days national average appointment wait time
  • OB-GYN: Typically 1-3 days with nearly 26% seeing an OB-GYN within 48 hours, compared to 31.4 days national average appointment wait time
  • Orthopedic surgery: Typically 1-3 days with nearly 38% seeing an orthopedic surgeon within 48 hours, compared to 16.9 days national average appointment wait time
  • Family medicine (PCP): Typically 1-3 days with 42% seeing a PCP within 48 hours, compared to 20.6 days national average appointment wait time

Looking Back to Look Forward
Unique, actionable insights into consumers’ health care behavior can be derived from 2022 data, providing a glimpse into what’s to come. Examining the industry’s journey affords the opportunity to predict what may continue to resonate in 2023.

For example, patients got back to regular care appointments after delaying or canceling appointments following the COVID-19 pandemic’s onset.

Additionally, telehealth usage declined in all specialties except mental health, moving virtual care toward being a specialty- and case-specific care modality. Consider these appointment trends from January-November:

  • 18% of appointments across all specialties were conducted via telehealth.
  • Excluding mental health, just 9% of booked appointments were conducted via telehealth.
  • 88% of mental health appointments were conducted via telehealth.

To find more information or book an appointment, visit Zocdoc.com.

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How truffles took root around the world



For centuries, the wild delicacy grew only in Europe. But improved cultivation techniques have enabled the pricey, odorous fungus to be farmed in new landscapes.

Every morning for three months of the year, Lola wakes at 8 and goes hunting. She races past oak trees, running at full speed through a 50-hectare field set in the southern end of the province of Buenos Aires, Argentina. The daily challenge — to find her elusive prey — never fails to excite Lola. She darts from place to place until faltering at last: 40 minutes into her day, she gets distracted or simply gives in to exhaustion.

Lola is a Brittany spaniel, and beneath her orange-spotted white coat is the agile body of a hunter. But her most important tool is her sense of smell. “Through training, dogs learn to recognize substances in their long-term memory — in this case, the smell of truffles,” says dog trainer Germán Escobar.

A graduate of the University of Buenos Aires who originally hails from Colombia, Escobar has trained Lola and the eight other dogs of the Argentine truffle farm Trufas del Nuevo Mundo, located in Espartillar, a small town of 785 inhabitants.

With 100 million to 300 million olfactory receptors in the nose — humans have only 5 million to 6 million — and a region in their brains dedicated to odor analysis that’s 40 times larger than that of Homo sapiens, trained dogs are able to do what no human can: Track one of the most valuable and desired delicacies, what’s called the “black diamond” of the kitchen, deep underground.

For centuries, truffles were found exclusively in European countries such as Spain, Italy and France, where they grow in the wild. But over the past 50 years, truffle production has experienced an incredible global expansion, thanks to cultivation techniques that have given rise to plantations in far-flung regions. Today, the United States, China, Greece and Turkey as well as countries across the Southern Hemisphere — Australia, New Zealand, South Africa, Chile and Argentina — have emerged as new producers of the famous fungi.

At least 180 species of truffle are known, although only about 13 are of any commercial interest: the black truffle (Tuber melanosporum, from the Latin tubera, meaning lump, hump or swelling) is one of the most celebrated and coveted. In July 2022, a kilo of black truffles went for 1,350 euros. Another highly valued species is the white truffle ( Tuber magnatum), also known as Trifola d'Alba Madonna (Truffle of the White Virgin), for which festivals are organized in Italy every year.

World truffle production has grown in recent years thanks to the increase in cultivation of this prized fungus, says a 2021 analysis published in the journal Forests. Spain leads world production of black truffles, with an annual average of 47 tons, followed by France and Italy.

The scent of truffles

Each of these natural jewels — black, rough, spherical, some as big as apples — is a miniature aroma factory. Some say that the black truffle smells like cold mountain air, or damp earth. Others say it evokes the smell of boiled potato, cauliflower, black olive, butter, mushroom, sulfur or garlic.

In 1825, the French gastronome Jean Anthelme Brillat-Savarin crowned it as “the jewel of the kitchen” and highlighted it as an aphrodisiac. Italian composer Gioachino Rossini went further and declared this mushroom the “Mozart of mushrooms.” And it was said that the English poet Lord Byron used to keep a truffle on his desk, confident that its perfume would stimulate creativity and attract the muses.

The truffle’s unique aroma is the result of a set of volatile organic compounds (VOCs) produced by the fungus. Far from being the result of a single molecule, the odors we perceive are produced by tens or hundreds of these invisible airborne particles. The structure of each VOC molecule is usually based on a hydrocarbon skeleton, with oxygen, nitrogen and sulfur as the most common atoms other than carbon or hydrogen; the molecules are all around us, and those that are generated by living organisms directly or indirectly influence the life of plants, insects and even humans by contributing to communication, mating and even the generation of flavors and aromas. For example, the smell of coffee is produced by at least a thousand chemical compounds that enter through our nostrils and meet our olfactory receptors. In strawberries, the number is more than 300 VOCs.

Of all fungi, truffles are among those that emit the highest amount of volatile organic compounds. More than 200 of these have been identified so far in various truffle species. Both black and white truffles pump out a mixture of alcohols, ketones, aldehydes, dimethyl sulfide, dimethyl disulfide, diacetyl, ethylphenol, furaneol and octenol.

The aroma potency varies according to truffle type,” wrote Italian chemist Elisabetta Torregiani and her team at the University of Camerino in a paper published in 2020 in the journal Molecules. “Black truffles are considered to be the most aromatic of all,” while summer truffles are the least, and white truffles are in the middle.

In addition, “the truffle’s aroma changes throughout its maturation,” says researcher Eva Tejedor Calvo, from the Center for Agricultural and Food Research and Technology of Aragon, in Zaragoza, Spain. Tejedor Calvo traveled to Argentina to study the aromatic differences between black truffles from that South American country and Spanish truffles. “We know that, depending on the locations within the same country, the aromas can change. They can also vary depending on the climate, depending on the soil, even between two trees in the same field.”

The aromatic potency of these fungi, which grow between 20 and 50 centimeters underground in complete darkness and attached to tree roots, serves a purpose. It is an evolutionary strategy for their survival as a species.

“Fungi are so smelly because they communicate chemically with other organisms in their environment,” explains Joan W. Bennett, a microbiologist at Rutgers University and coauthor of a report on aromatic diversity in the fungal kingdom in the 2020 Annual Review of Microbiology. “Fungi do not have nervous systems, so they must use other means of defense and dispersal. For example, some of the volatile compounds attract insects that clearly help with the dispersal of their spores. While hundreds of VOCs associated with molds and fungi have been chemically identified, we are only now beginning to understand their functionality.”

“Their delicious aroma and nutritional power attracts animals that benefit from eating them, and they carry them in their intestines and thus disperse them in faraway places,” explains Argentine mycologist Francisco Kuhar, a researcher at the Multidisciplinary Institute of Plant Biology of the National Scientific and Technical Research Council of Argentina, and coauthor of the book Crónicas del Reino de los Hongos ( Chronicles of the Kingdom of Mushrooms). “We can say that their exquisite aroma was selected to use us animals to disperse them.”

This sophisticated strategy of olfactory manipulation extends throughout all members of the mushroom family. In the case of truffles, they use it in a similar way as that developed by flowers that rely on insects and birds as dispersers and pollinators. “Unlike most fungi that spread their spores through the air, truffles are found underground and require animals to help with their dispersal,” says Bennett. “It is believed that the truffle odor evolved because volatiles can diffuse through the soil and attracts animals to eat and further disseminate their spores. This production of pungent cocktails consisting of volatile compounds draws a set of small animals that truffles have coevolved with, or at least adapted to, in order to facilitate spore dispersal.”

Pigs are one of these animals. Since the 15th century, black truffle hunters in Italy and France made use of trained pigs, especially females, which were particularly attracted to the intoxicating smell of the truffle that emanates a compound chemically similar to androstenol, a sex pheromone that is also synthesized in the testicles of wild boars.

The problem is these animals are not only mesmerized by the truffle’s aroma but also by its taste, and it is very difficult to train them not to devour it. For this reason, truffle pigs were banned in Italy in 1985. There, professional truffle hunters (known as tartufai) must be licensed. They roam the fields with trained dogs and their knowledge, which has been passed down orally for centuries, is included in UNESCO’s Representative List of the Intangible Cultural Heritage of Humanity.

From wild to cultivated

In the early 1880s, the King of Prussia asked the forest biologist Albert Bernhard Frank to study truffles. Wilhelm I adored the fungus’s delicate flavor and wanted the researcher to develop a way to produce truffles on a commercial scale.

But Frank failed in attempt after attempt, as did all the other enthusiasts who followed him. Still, the dedicated and meticulous botanist’s many years of study were not in vain, as plant ecologist David W. Wolfe recalls in his book Tales from the Underground: A Natural History of Subterranean Life: Frank noticed that truffles never grew independently, but always appeared near oak, hazel, poplar and beech trees. He surmised that the truffle was a parasite. Later he figured out that the two organisms work in partnership. Trees depend on fungi to help gather essential minerals, and truffles, which cannot photosynthesize, receive nutrients from the tree’s roots. In 1885, Frank described this symbiotic relationship with the term “mycorrhiza” (from the Greek myco, meaning fungus, and rhiza, meaning root).

Since then, intimate associations between plants and fungi have been identified in fossils dating back more than 450 million years. Today, more than 200,000 plant species are known to harbor mycorrhizal fungi.

“Mycorrhizal fungi extend the plant root systems and these fungi ‘forage’ the soil for nutrients, especially nitrogen and phosphorus. They can also confer drought and pathogen resistance,” notes University of New Hampshire ecologist Serita D. Frey, who describes this symbiotic link in a paper published in the 2019 Annual Review of Ecology, Evolution, and Systematics. “In exchange for these vital services, the plant provides the fungus with energy in the form of sugars which the plant makes through photosynthesis.” And she adds that some plants cannot survive without their fungal partner. “They have become dependent on the fungi for nutrition.”

In his book Truffle Hound: On the Trail of the World’s Most Seductive Scent, with Dreamers, Schemers, and Some Extraordinary Dogs, Rowan Jacobsen points out that truffle cultivation remains as much an art as a science. Each farm follows its own techniques, some closely guarded secrets. The truffle’s journey from spore to plate is fraught with biological uncertainty, economic competition and logistical headaches.

Hundreds of conditions and variables must align: This finicky fungus grows only when environmental conditions (temperature range, well-marked seasons, rainfall or controlled irrigation) and soil conditions (acidity, humidity, minerals such as phosphorus and potassium) are exactly right.

Truffles were harvested from the wild until new inoculation techniques developed in France in the 1970s opened the door to growing the species in managed plantations. “In a nursery, it’s first a matter of attaching the fungus spore to the roots of the tree,” explains Faustino Terradas, sales manager of Trufas del Nuevo Mundo. “The spore then begins to germinate and generate a mycelium, or a fungus root, that is going to cover the root of the tree. Then it is taken to the field and planted.”

During the first few years, the tree’s health is cared for, the acidity of the soil is controlled, and water is supplied through irrigation in order to generate the conditions for the underground development of the truffle. “During the spring, the primordia or small truffles, red on the outside and white on the inside, are generated,” adds Terradas. “From then on, it matures. In autumn it widens. And in the winter is when it finishes ripening.”

Yields in France have fallen dramatically for more than a century — first, because of the closures of truffle fields during the World Wars, and then because of decreasing rainfall and rising temperatures.

This situation has boosted the truffle’s expansion. Truffles now inhabit continents where they were not found a hundred years ago. In recent decades, attempts to domesticate them have spread around the world: After centuries of being a delicacy exclusive to Europe and being dispersed by dogs, pigs, squirrels and insects, it is now humans, motivated by their special aroma, who are driving their planetary migration.

The first US black truffle was harvested in Northern California in 1987. In 2009, Chile became the third country in the Southern Hemisphere to cultivate truffles, after New Zealand and Australia. According to mycologist Ian Hall of the Royal Society of New Zealand, who developed methods for the first truffle plantations in the Southern Hemisphere, there may be as many as 1,000 truffle farms outside of Europe.

In Argentina, where harvesting takes place in the colder months of June, July and August, Trufas del Nuevo Mundo got its first “black diamond” — weighing in at 69 grams — in 2016. Since then, this venture has expanded to 20,117 mycorrhizal trees and exports truffles to the Northern Hemisphere when they are out of season in Europe.

The truffle “has a lot of history, but there is little research,” says Terradas. “Wheat has been planted for more than 4,000 years, but the truffle only 50 years ago. We still have a long way to go to understand the truffle and its development.”

Article translated by Debbie Ponchner

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This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.

OPINION: Volcanologists warn that magma-filled vents evolve over time, leading to an underestimation of the number that might erupt — especially those capable of the biggest explosions

Many people know that Naples is built on two very active volcanoes, Vesuvius and Campi Flegrei, and that it is one of the cities most at risk from volcanic activity in the world.

But practically nobody knows that Rome is also built right in between two major explosive volcanoes: Sabatini to the north and Colli Albani (or Alban Hills) to the south. These haven’t erupted within historic memory — so Sabatini is considered “extinct” and no one worries much about Colli Albani. Yet both are hot and emitting volcanic gases. There is magma there, but deeper down in the crust, out of sight. Our analysis of the latest data indicates that these are long-lived volcanoes potentially brewing new volcanic eruptions.

These volcanoes aren’t alone. There are hundreds of volcanoes around the world that scientists consider dead but that may actually be active and should be monitored. Researchers have estimated that more than 800 million people live near active volcanoes, but we think hundreds of millions more people may be unknowingly exposed to volcanic explosions. 

As volcanologists, we have proposed an innovative way to determine whether a volcano is likely to reactivate or not: Take into account not just when it last erupted but also the thermal state of its plumbing system. This isn’t the only — nor even necessarily the best — way to do this. But with our new Volcanic Activity Index, we can identify volcanoes that have generally escaped attention but deserve close monitoring (see Box). 

It is generally thought that there are about 1,500 potentially active volcanoes around the world, about 500 of which have erupted in historical times. Some, like Etna in Italy and Mount St. Helens in Washington state, are extensively studied. But only a limited number of volcanoes have any monitoring at all, partly because of a lack of funds. As a result, many eruptions catch people by surprise — like Chaitén Volcano in southern Chile, which erupted explosively in 2008 after 9,000 years of silence, covering the nearby town of Chaitén with more than a meter of muddy ash. 

This has long been an acknowledged problem, and many volcanologists have proposed ways to improve the situation. In the 1990s, which was the International Decade for Natural Disaster Reduction, researchers identified 16 volcanoes worthy of particular attention because of their history of large explosive eruptions and proximity to densely populated areas. Scientists have suggested ways to use satellites and drones to track activity and have called for more local on-the-ground monitoring. But we will also need to design new approaches to identify sleeping giants and look deep into the belly of volcanoes.

Right now, surprisingly, there isn’t a particularly scientific way to define the activity of a volcano. The main data volcanologists consider are the date of the last eruption and certain measures of the known eruptive history (such as the frequency and size of past eruptions). This is often biased by which cultures have kept a record of eruptions or which areas have been studied, and it ignores how volcanoes evolve over time.

Volcanoes change as they grow older. The long-term seeping of magma into the Earth’s crust from deeper below changes the crust’s temperature and physical properties. Younger volcanoes tend to sit above a cooler crust that can’t store a lot of magma; older volcanoes have a warmer crust that can support larger quantities of magma, and so they tend to produce bigger eruptions with longer periods of rest in between. In other words, an older volcanic system needs to have been quiet for a lot longer before it should be considered extinct. You can have a large, dangerous volcano sitting in a kind of vegetative state, with its magma lurking far below, undetected. This magma can rapidly migrate to shallow chambers and the volcano can erupt. 

We created the Volcanic Activity Index because we couldn’t find a good index that takes this aging effect of volcanoes into account. Our index produces a single number that compares the activity of any one volcano to all the others out there, based on when it last erupted, how much magma the volcano has erupted in total over its entire history, and the average rate at which it has erupted over its whole life.

This analysis throws up some surprises. For example, our analysis shows that Italy’s Colli Albani has a higher activity index than the famous — and clearly still active — Yellowstone Caldera volcano in Wyoming.

We have a problem, though: Often, we don’t know how old a volcanic system is. The oldest dated eruption of the Campi Flegrei caldera in Naples, for example, is 80,000 years ago; however, recent investigations have shown that this volcano started erupting at least a few hundred thousand years ago. This would significantly change the activity index for this system. Our analysis highlights what we still need to know. If there is a big campaign to measure these factors around the world, the list of worrying volcanoes will likely change.

What should we do with this list? Many of these volcanos seem to be quiet at the surface, but we don’t know what’s going on deep down below. That’s what we need to figure out next. Right now, researchers use seismic tomography (watching how seismic waves travel through the Earth) or electrical conductivity to try to peer into the depths. However, these methods generally can’t see anything more detailed than about 1 cubic kilometer, and this gets worse with depth, exactly the regions from where we need more information.

We need a big push in the scientific community to find new and better ways to see 15 to 20 kilometers down into the heart of a volcano. We think this would provide much longer warning times to anticipate the reactivation of dormant volcanoes (like Chaitén).

How this information is used is ultimately up to locals. People have been living around active volcanoes since the dawn of humankind; it is extremely difficult to weigh an uncertain future risk against the needs of day-to-day life. It is not our job to tell people what to do, whether to stay or leave. But the people living near such volcanoes deserve a scientific evaluation of the potential risks they face. We hope that our index will help.

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This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.



OPINION: To justify their existence, they must make conservation their top priority

When I was young, my parents took us to a zoo: the kind where you could see animals locked up in cages. I remember looking in admiration at a pair of bears in a cage, stretching out their paws for food. Things have changed. My kids would be horrified to see animals in jail like that. Today, we expect animals to be held in more natural settings, and for zoos to do more to make the world a better place. In order to justify the animals’ captivity, we expect zoos to help with conservation.

Zoos can host great conservation work. Sometimes they act as a kind of Noah’s ark to hold and protect endangered animals. There are about 40 animal species listed as “extinct in the wild”; they exist mainly in captive collections, including at zoos. These collections are used for study, to start breeding programs and, when possible, to reintroduce the animals to the wild.

But not enough zoos do enough of this. I support the recommendation made by some researchers that zoos should assign at least 10 percent of their income to biodiversity conservation. Sadly, a 1999 study from the Association of Zoos and Aquariums showed an average expenditure of only 0.1 percent. That’s 100 times less.

Of course, some zoos do a lot. Perth Zoo in Western Australia, for example, reported in 1999-2000 that it spent more than US$1 million breeding seven threatened species for reintroduction (including the western swamp tortoise, the chuditch marsupial, and the striped numbat), compared with their income of nearly $6 million. In other words, they spent at least 18 percent of their revenue on conservation. According to a 2015 World Association of Zoos and Aquariums report, $350 million is raised annually for wildlife conservation by global zoos and aquariums. That’s about the same as what WWF International — one of the most famous institutions in biodiversity conservation — currently spends on conservation programs each year.

Zoos have helped to reintroduce plenty of animals to the wild, including the black-footed ferret in the US, Przewalski’s horse in Mongolia, the Guam rail (a flightless bird), and island fox of California’s Channel Islands. Zoos can also help during a crisis: When bushfires raged across Australia in the summer of 2019-2020, Zoos Victoria was part of a state-led response to help wildlife.

If zoos were totally dedicated to the function of conservation, we might expect them to mostly house threatened species. But it’s clear that almost all zoos host non-threatened species in much greater numbers. Many zoos are focused on the big mammals and birds that draw audiences and help the zoos to make money, including elephants and giraffes; quite a lot of zoos exist solely as an entertainment business. In this day and age, I say that’s inappropriate. The possible detriment to the individual animals’ welfare is too high a price to pay for entertainment alone.

That’s not to say that zoos shouldn’t be a business at all. The care and feeding of animals can be extremely expensive: Food expenses for mammals in England’s Chester Zoo (which houses tens of thousands of animals) exceed $700,000 per year. I believe that it’s worthwhile for zoos to open their doors to the public to recoup some of this money, and to keep animals beyond the ones they are breeding or studying for conservation reasons in order to attract interest and attention — so long as the animals are kept in morally acceptable conditions that guarantee their welfare.

Opening doors to the public, of course, has a second benefit: education. In the US, 183 million people went to zoos and aquariums in 2022; nearly ten times more than attended professional football games. The opportunity for education is huge. Yet a lot of people don’t bother reading educational signs. And while animal shows are popular and good at conveying information, they can also, controversially, involve animal training. Many studies show that people tend to retain knowledge about animals from zoo visits, but whether that translates into pro-environmental action is debatable.

It seems intuitive to me that visiting animals in real life helps to foster an appreciation for the natural world. Virtual-reality goggles and movies about wildlife are worthwhile, but not the same. A friend of mine who works in the Amazon puts it this way: “To love the jungle, you need to smell the jungle.” Full immersion in real-life environments is a powerful experience that’s hard to replicate.

Some zoos have adopted the promising One Plan approach, which encourages zoos to work in collaboration with researchers and local communities on conservation activities. One good example is Zoos Victoria’s conservation breeding program for the Australian eastern barred bandicoot.

All zoos should make conservation their top priority, which will inevitably be accompanied by education and research. Without that, a zoo becomes just a business: one the world would be better off without.

This article originally appeared in Knowable Magazine, an independent journalistic endeavor from Annual Reviews.